Often used for:
Depression, anxiety, OCD, panic disorder, PTSD, PMDD, other mood issues
What is sertraline?
Sertraline is an SSRI antidepressant that increases serotonin levels to regulate mood. It may be administered in the clinic, hospital, or at home.
Sertraline at home
- Tablets and capsules may be taken with or without food; take with food if stomach upset occurs.
- Swallow capsules whole.
- Mix liquid doses with water, ginger ale, lemon-lime soda, lemonade, or orange juice and take immediately.
- Give missed doses as soon as possible unless near the next dose; do not double.
- Store at room temperature in a dry place.
Possible side effects
- Dry mouth
- Abdominal pain
- Nausea or vomiting
- Fatigue or weakness
- Dizziness
- Sleep problems
- Headache
- Sexual dysfunction
- Increased sweating
- Tremor
- Constipation or diarrhea
- Indigestion
- Changes in appetite or weight
- Bleeding or easy bruising
- Suicidal thoughts or behaviors
- Allergic reactions (rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in the throat, swelling of face or neck)
- Not all patients experience these effects. Report all symptoms.
Tips for patients and families
- Discuss all questions with the health care provider or pharmacist.
- Allow several weeks for full benefits and contact the care team if symptoms worsen.
- Do not stop the medicine abruptly; withdrawal symptoms can occur.
- Monitor closely for mood changes or suicidal thoughts.
- Use caution with activities requiring alertness.
- Discuss fertility considerations with the care team.
- Inform the care team if sexually active, pregnant, or breastfeeding.
